Chilblains (inflammatory lesion of the feet or hands) have been reported with an unusual frequency during the confinement period, most commonly in children, teenagers and young adults. The aim of the ECCES study is to find out whether these manifestations of chilblains can be linked to the SARS-CoV-2 coronavirus. For this, an epidemiologic study will compare two types of family (or more precisely people who were confined together in March-April-May): * "case family" in which at least one of the members had chilblains * "comparator family" in which none of the members had chilblains Environment (home lockdown) of the two types of family will be analyzed. Each member of the "family" will be suggested doing a serological test.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
269
10mL blood sample
CHU Angers
Angers, France
CHRU Brest
Brest, France
CHU Nantes
Nantes, France
CHU Rennes
Rennes, France
CHRU Tours
Tours, France
Level of viral exposure in "case family" compared to "comparator family"
Time frame: Through study completion, an average of 3 months
Comparison of seropositivity rates in subjects with chilblains and their age-matched controls
Time frame: Through study completion, an average of 3 months
Comparison of SARS-CoV-2 seropositivity rates among members of case (subject with chilblains) and control (subject without chilblains) outbreaks
Time frame: Through study completion, an average of 3 months
Antibody avidity and differentiated IgG and IgM assay by subject in the homes
Time frame: Through study completion, an average of 3 months
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