The EXAMINATION trial was a superiority trial that compared everolimus-eluting stents (EES) versus bare-metal stents (BMS) in an all-comer ST-segment elevation myocardial infarction (STEMI) population. The patient-oriented endpoint was not superior at 1-year, but it was at 5-year. However, very-long term follow-up is unknown. The study had an independent Clinical event Committee (CEC). All events were adjudicated by an independent clinical committee, according to the Academic Research Consortium 1.
Study Type
OBSERVATIONAL
Enrollment
1,498
Everolimus Eluting Coronary Stent System (Everolimus Arm) implantation
Cobalt chromium balloon-expandable stent (non-drug-eluting stent Arm) implantation
Azienda Ospedaliera Bolognini
Seriate, Bergamo, Italy
Azienda Ospedaliero Universitaria S. Anna di Ferrara
Ferrara, Italy
Erasmus MC, Rotterdam
Rotterdam, Netherlands
Hospital de la Santa Creu i Sant Pau
Barcelona, Catalonia, Spain
Hospital Clínic i Provincial de Barcelona
Barcelona, Catalonia, Spain
Hospital de Bellvitge
Barcelona, Catalonia, Spain
Complejo Hospitalario U. A Coruña
A Coruña, Galicia, Spain
Hospital Álvaro Cunqueiro
Vigo, Galicia, Spain
Hospital Son Dureta
Palma de Mallorca, Mallorca, Spain
Hospital General de Alicante
Alicante, Valencia, Spain
...and 1 more locations
Patient-oriented Composite Endpoint (PoCE)
Rate of composite endpoint of all-cause death, any myocardial infarction, and any revascularization. Defined according to the Academic Research Consortium 1.
Time frame: 10 years
Device-oriented Composite Endpoint (DoCE)
Rate of composite endpoint of cardiac death, Target vessel myocardial infarction, and Target lesion revascularization. Defined according to the Academic Research Consortium 1.
Time frame: 10 years
Rate of all cause and cardiac mortality
Defined according to the Academic Research Consortium 1.
Time frame: 10 years
Rate of recurrent myocardial infarction
Defined according to the Academic Research Consortium 1.
Time frame: 10 years
Rate of target lesion revascularization
Defined according to the Academic Research Consortium 1.
Time frame: 10 years
Rate of stent thrombosis
Defined according to the Academic Research Consortium 1.
Time frame: 10 years
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