A Study to Describe Routine Treatment Pathways in Participants With Major Depression and Active Suicidal Ideation With Intent in Italy

Inclusion Criteria: * Participant must meet Diagnostic and Statistical Manual of Mental Disorders (5th edition) (DSM-5) diagnostic criteria for single episode or recurrent Major Depressive Disorder (MDD), based upon clinical assessment * In the physician's opinion the current depressive episode is moderate-to-severe in terms of severity. * In the physician's opinion, acute psychiatric hospitalization is clinically warranted due to participant's current active suicidal ideation with intent * Participant must be capable of discernment * Participant must be able to read and write in the Italian language * Participant must have signed the informed consent form (ICF) indicating that he/she understands the study purpose and is willing to participate in the study * Participant is in the site's catchment area, as evaluated by the Investigator Exclusion criteria: * Participant currently (that is, at the time of enrolment and based upon clinical assessment) meets DSM-5 criteria for psychotic disorder, bipolar or related disorders, antisocial personality disorder, borderline personality disorder, intellectual disability, autism spectrum disorder, dementia * Participant meets the DSM-5 severity criteria for moderate or severe substance or alcohol use disorder (except for nicotine or caffeine) within the 6 months before enrolment, based upon clinical assessment * Participant has participated in or is currently enrolled in any clinical trial with experimental treatments within the current major depressive episode