Epidemiological data have related particulate matter (PM), nitrogen dioxide (NO2) and ozone (O3) to COVID-19 morbidity and mortality at the population level. Air pollution may be related to an increase in the COVID-19 severity and lethality through its impact on chronic diseases such as cardiovascular and respiratory diseases and diabetes that are also the main comorbidities associated with COVID-19. Epidemiological studies using individual data are needed to provide more precise estimate of the association between air pollution exposure and COVID-19. In this multicenter prospective study, the investigators will analyze the number of deaths in COVID-19 confirmed cases in geriatric patients according to long-term exposure to air pollution, taking into account confounders such as diabetes, hypertension, age, and BMI. Exposure to air pollution will be estimated as the mean concentration of air pollutants at the residential address during the previous two years. In addition, the investigators will explore the relationship between short-term variations in air pollutants, relative humidity, temperature, UV radiations, pollen and the occurrence of COVID-19.
Study Type
OBSERVATIONAL
Enrollment
660
Unité de neurologie-gériatrie, Hôpital Erasme, Cliniques Universitaires de Bruxelles
Brussels, Belgium
Unité de soins palliatifs gériatriques, Centre Hospitalier Départemental de Bischwiller
Bischwiller, France
Service de Gériatrie, Centre Hospitalier Départemental de Vendée
La Roche-sur-Yon, France
Service de médecine aigüe gériatrique, Hôpital Nord Laennec, Hôpitaux Universitaires de Nantes
Nantes, France
Service de Gériatrie, Hôpitaux Bichat et Bretonnaux, Assistance Publique des Hôpitaux de Paris
Paris, France
Service de Médecine Interne et Gériatrie, Hôpitaux Universitaires de Reims
Reims, France
Service de Gériatrie, Hôpital de la Robertsau, Hôpitaux Universitaires de Strasbourg
Strasbourg, France
Service de médecine gériatrique, Hôpitaux Universitaires de Tours
Tours, France
COVID-19 related-mortality
Association between COVID-19 related-mortality and air pollutants concentrations estimated at the residential address of geriatric patients during the last 2 years ( from 2018/01/01 to 2019/12/31)
Time frame: COVID-19 mortality between 2020/01/01 and 2020/06/01
COVID-19 confirmed cases
Association between short- term variations in air pollutants, temperature, humidity, UV, pollens and the occurrence of COVID-19 confirmed cases. Short-term variations are defined as changes in air pollutants concentrations, temperature, humidity and pollen during the 20 days preceding the hospitalization.
Time frame: COVID-19 confirmed cases between 2020/01/01 and 2020/06/01
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