Human Placental Mesenchymal Stem Cells Treatment on Diabetic Foot Ulcer

Inclusion Criteria: * Age ≥ 18 and Age ≤ 75 * Type 1 or type 2 diabetes mellitus, glycosylated hemoglobin ≤ 9.0% * Diagnosed as condition of diabetic foot ulcer, Wagner grade at 1 or 2 after clinical treatment * Full understand the informed consent form, and signed it voluntarily Exclusion Criteria: * Pregnant or breast-feed women or plan to pregnant or fail to take an efficient contraception * Be allergic to any component of the drug or showed allergic constitution * Showed a sign of systemic infection, or with complication of ethmyphitis, or osteomyelitis indicated by MRI * Have malignancy in the ulcer pathology test, or have a history of malignant tumor * Unable to clean the wounds due to the formation of tract between the ulcer and other condition * Infected with hepatitis B virus (HBV), hepatitis virus C (HCV), human immunodeficiency virus (HIV), or treponema pallidum * Alanine transaminase (ALT) or aspartate transaminase (AST) exceeds 2.5 times of the normal value, or Cr\>200 μmol/L * Have a history of apoplexy, unstable angina pectoris, myocardial infarct * Have a psychiatric history, drug abuse or alcohol abuse history * Had participated in any other clinical trials in the past 3 months * Any other circumstances judged by the researchers disqualify the patient to participate in the trial