180 people from the medical staff and high-risk people in Baqiyatallah Hospital, who are in close contact with patients, will enter the study. Participants will be divided into two intervention groups and one control group. The control group will use the full protective equipment assigned to the treatment staff. In addition to protective equipment, the first intervention team will receive a daily diet of 200 mg hydroxychloroquine tablets. The second intervention team, while observing and using the complete protective equipment, will place a thin layer of Mucodentol gel in the vestibular area of the mouth daily, every 6 to 8 hours. At the beginning of the treatment, qualified people will participate in the study while recording demographic and clinical information, PCR test will be performed, and if they have negative PCR, they will be in one of the 3 study groups. During the study, if the symptoms of the disease occur in each of the participants, the test will be taken again. If the test is positive, the person will withdraw from the study, and the patient's information will be recorded. Finally, the people present in the study will be tested for PCR, and the results of the disease and the side effects of the drugs will be compared.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
200 mg of hydroxychloroquine daily for participants in the intervention group 1
Intervention Group 2 participants will place a thin layer of Dentol gel in the vestibular area of the mouth every 6 to 8 hours.
Personal protective equipment such as masks, gloves, protective shields
Mohammad Sadegh Bagheri Baghdasht
Tehran, Iran
PCR test
Laboratory PCR testing can help diagnose the disease
Time frame: up to 1 month
Laboratory Treatment Response
Normal blood cell count and CRP count (normal laboratory range)
Time frame: up to 1 month
drug reactions Adverse
Complications in both groups should be evaluated and evaluated during treatment.
Time frame: up to 1 month
Allergic drug
There will be known allergic reactions to the drugs.
Time frame: up to 1 month
Radiological Treatment Response
CT scans help determine how much the lungs are affected by COVID-19.
Time frame: up to 1 month
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