Evaluate the Effects of Food on the Pharmacokinetics of Fadanafil in Healthy Subjects

Inclusion Criteria: * Healthy male subjects 18-45 years old, inclusive. * Body weight ≥50kg and Body Mass Index: 19.0\~26.0 kg/m2, inclusive * The vital signs (body temperature, systolic and diastolic blood pressure, heart rate and respiration) were in the normal range, and the normal value range of each vital sign was: (1) body temperature (underarm) 36.3 \~ 37.2 ℃; (2) 90mmHg ≤ systolic blood pressure \< 140mmHg; (3) 60mmhg ≤ diastolic blood pressure \< 90mmHg; (4) 50th / min ≤ heart rate ≤ 90th / min. * Before the test, a comprehensive physical examination, laboratory examination and other auxiliary examinations were carried out, and the results were normal or abnormal but of no clinical significance. The ECG QTcF \< 450 ms. * Subjects should be willing to take appropriate contraceptive measures during the period of taking the study drug and within 6 months after discontinuation to avoid pregnancy of their partners. * Subjects understand and will comply with the study procedure, participated voluntarily and signed the informed consent. Exclusion Criteria: * Subjects who have a history of clinical significant drug allergy (especially those who are known or suspected to have a history of allergy to any PDE-5 inhibitor or its components) or a history of atopic allergic diseases (asthma, urticaria, eczema dermatitis) or severe allergic constitution. * History of clinically significant ECG abnormality or family history of long QT syndrome (grandparents, parents, brothers and sisters). * Subjects with severe systemic diseases, such as respiratory, blood, endocrine, cardiovascular and cerebrovascular diseases or mental disorders. * Subjects with concominant diseases that may affect drug absorption, distribution, metabolism, excretion and safety evaluation, or reduce compliance. * The test results of human immunodeficiency virus (HIV) antibody or hepatitis B surface antigen (HBsAg) or hepatitis C virus (HCV) antibody or syphilis are positive. * Subjects who have used over-the-counter drugs, health products, Chinese herbal medicine or traditional Chinese medicine within 2 weeks before screening, or who are taking foods that affect CYP3A4, such as grapefruit or drinks containing grapefruit (except those who occasionally take paracetamol orally, but the total maximum dose cannot exceed 1g, and the drug is not allowed to take orally within 48 hours prio to first dose). * Subjects who had used any prescription drugs (especially CYP3A4 inhibitors, nitrates, α receptor blockers, drugs potential to cause QT interval prolongation, etc.) within 4 weeks before screening.