The purpose of this study is to assess levels in blood plasma of BMS-986278 and the food effect in healthy participants.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
24
Specified dose on specified days
Specified dose on specified days
Specified dose on specified days
ICON (LPRA) - Salt Lake
Salt Lake City, Utah, United States
Maximum plasma concentration (Cmax) of BMS-986278
Time frame: Up to 5 days
Area under the concentration-time curve from time 0 (dosing) to the time of the last quantifiable concentration observed (AUC(0-T) of BMS-986278
Time frame: Up to 5 days
Area under the concentration-time curve from time 0 (dosing) extrapolated to infinity AUC (INF) of BMS-986278 from the respective test treatments
Time frame: Up to 5 days
Incidence of Adverse Events (AEs)
Time frame: Up to 29 days
Incidence of Serious Adverse (SAE's)
Time frame: Up to 57 days
Incidence of AEs leading to discontinuation
Time frame: Up to 29 days
Incidence of clinically significant changes in vital signs: Blood pressure
Time frame: Up to 48 days
Incidence of clinically significant changes in vital signs: Heart rate
Time frame: Up to 48 days
Incidence of clinically significant changes in vital signs: Respiratory rate
Time frame: Up to 48 days
Incidence of clinically significant changes in vital signs: Body temperature
Time frame: Up to 48 days
Incidence of clinically significant changes in electrocardiogram (ECG) parameters
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Time frame: Up to 48 days
Incidence of clinically significant changes in physical examination findings
Time frame: Up to 48 days
Incidence of clinically significant changes in clinical laboratory results: Clinical chemistry tests
Time frame: Up to 48 days
Incidence of clinically significant changes in clinical laboratory results: Urinalysis tests
Time frame: Up to 48 days
Incidence of clinically significant changes in clinical laboratory results: Hematology tests
Time frame: Up to 48 days