The Study of Drug 601 in Patients With Wet Age-related Macular Degeneration (wAMD)

Inclusion Criteria: 1. Sign informed consent form and willing to be visited at the time specified in the trial; 2. Age ≥45 years and age ≤ 80 years; 3. The study eye must meet the following criteria: * Diagnosis of wAMD; * The presence of an primary or recurrent active choroidal neovascular (CNV) lesions in subfovea and para-fovea secondary to AMD; * Total area of all types of lesions ≤30mm2 (12 optic disc areas) * Best EDTRS letter score between 19 and 78(Snellen equivalent of 20/400 to 20/32); * No optometric media opacity and pupil shrinkage. 4. Best EDTRS letter score ≥19 (Snellen equivalent of 20/400 or better) in the fellow eyes. Exclusion Criteria: Any of the following eye conditions: 1. Any eye has active ocular infections (e.g.,blepharitis, keratitis, scleritis, conjunctivitis); 2. History of vitreous hemorrhage in the study eye within 2 months before screening; 3. scarring, fibrosis, or atrophy below with fovea in the study eye; 4. Received any drug treatment for CNV within 120 days prior to screening; 5. History of any following surgery in the study eye (e.g. PDT, macular transposition, Glaucoma filtration, subfoveal photocoagulation, vitrectomy and transpupular hyperthermia, and other surgery at the submacular or others for AMD) within 3 months before screening; 6. CNV in the study eye associated with other ocular diseases such as pathologic myopia, eye trauma, etc 7. History or present of uncontrolled glaucoma, history of glaucoma filtering surgery in the study eye; 8. Subretinal hemorrhage in the study eye, and the bleeding area ≥ 50% area of the total lesion; 9. History of rhegmatogenous retinal detachment or macular hole retinal detachment (stage 3 or 4) , retinal detachment, retinal pigment epithelium tear or macular area traction and macular area preretinal membrane and PCV in the study eye; 10. The study eye has no lens( except intraocular lens) or posterior capsular rupture of the lens; Any of the following general condition are present: 11. Medicines with toxicity to the lens are being used or may be used during the study period; 12. History of allergy to fluorescein sodium and allergies to protein products for treatment or diagnosis, history of allergy to more than two drugs and/or non-drug factors, or suffering from allergic diseases now. 13. History of surgery within 1 months before screening; and/or unhealed wounds, ulcers or fractures currently; 14. Suffering from systemic infections and requiring oral, intramuscular or intravenous medication; 15. History of stroke, myocardial infarction within 6 months before screening; 16. Active diffuse intravascular coagulation and obvious bleeding tendency within 3 months before screening; 17. Systemic immune diseases; 18. Uncontrolled blood pressure control ; 19. Diabetic patients with uncontrolled blood sugar; 20. Any uncontrolled clinical problems (such as severe mental, neurological, cardiovascular, respiratory and other systemic diseases and malignant tumours); Any of the following laboratory tests abnormalities(23-25): 21. Renal function impairment (Cr is 1.5 times higher than the upper limit of normal values in the local laboratory) Liver dysfunction (ALT or AST is 2 times higher than the upper limit of normal value in the local laboratory). 22. Abnormal coagulation function (prothrombin time \>= the upper limit of normal value for 3 seconds) and activated partial thromboplastin time \>= the upper limit of normal value for 10 seconds); Patients with childbearing age with any of the following conditions: 23. Those who do not use effective contraceptive measures; The following are not excluded: 24. Pregnancy and lactation women (pregnancy is defined as urinary pregnancy test positive in this study); Any other conditions: 25. Participation in any other drug clinical trials (except vitamins and minerals) in the past 1 month before screening ; 26. Researchers think it needs to be ruled out.