The participants are being treated with Tumor Treating Fields (TTFields) for malignant glioma, and this type of treatment may cause skin-related side effects. This study will test whether using clindamycin and triamcinolone topical lotions can prevent skin-related side effects of TTFields.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
48
phosphate 1% solution triamcinolone 0.01% at every array change (or approved equivalent)
triamcinolone acetonide 0.01% lotion triamcinolone 0.01% at every array change
Northwestern University
Evanston, Illinois, United States
Tufts Medical Center
Boston, Massachusetts, United States
Washington University School of Medicine
St Louis, Missouri, United States
Hackensack Meridian Health
Number of patients without grade 2 or higher skin toxicity
device-related skin adverse events by investigator assessment.
Time frame: up to 120 days
skin-related quality of life
using the PRO-CTCAE for rash, ulcer, and pruritus.
Time frame: up to 120 days
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Hackensack, New Jersey, United States
Memorial Sloan Kettering Cancer Center Suffolk - Hauppauge (All Protocol Activities)
Hauppauge, New York, United States
Memorial Sloan Kettering Cancer Center
New York, New York, United States
Columbia University
New York, New York, United States
University of Cincinnati Medical Center
Cincinnati, Ohio, United States