Efficacy and Safety of Lacidofil® STRONG as an Adjuvant for Helicobacter Pylori Treatment in Non-ulcer Dyspepsia

Inclusion Criteria: * Thai patients consulting for dyspeptic symptoms. * Aged between 18 and 65 years. * Diagnosed for H. pylori infection using RUT and 13C-UBT. * H. pylori treatment naïve. * Able to provide informed consent. * Willing to maintain their usual physical activity regime and diet, as well as discontinuing the consumption probiotic-containing and fermented foods. Exclusion Criteria: * Upper gastrointestinal bleeding. * Presence of duodenal or gastric ulcers, MALT lymphoma, gastric resection, gastric malignancy as per endoscopy (visual assessment). * Current intake of antibiotics, such as amoxicillin, clarithromycin, metronidazole or fluoroquinolone. * Use of probiotics in the past month, and unwilling to undergo a 2-week washout period before the study. * Use of NSAIDs, aspirin or other anti-inflammatory drugs within 1 week (for occasional use) or 3 weeks (for chronic use) of inclusion. * Contraindication for gastric biopsy (e.g., coagulopathy). * Any history of allergy for penicillin, levofloxacin, clarithromycin or rabeprazole. * Receiving proton pump inhibitor within 4 weeks or receiving any antibiotics or bismuth within 2 weeks of trial initiation. * Being pregnant or breastfeeding. * Having severe underlying disease including end-stage renal disease requiring hemodialysis or peritoneal dialysis (GFR \< 15), cirrhosis with Child-Pugh classification grade C, immuno-compromised host with AIDS, malignancy and/or cerebrovascular or cardiovascular disease. * Taking anticoagulants (e.g., warfarin) or anti-platelet agents (e.g., clopidogrel) * Previous gastric surgery. * Having underlying heart disease, including congenital long QT syndrome. * Unwilling to stop taking over-the-counter, natural or herbal medicines for dyspeptic or gastrointestinal symptoms (e.g., antidiarrheal, anti-emetics, antacids) during the intervention period (6 weeks). * Milk and soy allergy. * Lactose intolerance.