The objective of this study is to measure the effect of Iodine complex in treating the COVID-19 patients to clear viral load of SARS-CoV-2 along with reduction in severity of symptoms and length of hospitalization of patients with COVID-19.
The proposed study is a placebo-controlled, add-on, randomized trial using parallel group designs. This is a close-label and adaptive, multi-centered design with 1:1:1:1 allocation ratio and superiority framework.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
200
Iodine Complex capsule (200mg) will be given three times a day
Iodine Complex syrup form (40ml) will be given three times a day
Empty capsule will be given as placebo
Shaikh Zayed Hospital
Lahore, Pakistan
RECRUITINGqRT-PCR
Time taken for viral load clearance
Time frame: 14 days
HRCT chest
Time taken for radiological improvement
Time frame: 14 days
Severity of Symptoms
Time taken for symptomatic response in patients
Time frame: 14 days
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Iodine Complex spray form 2 puffs will be given three times a day