Infections are common and associated with poor outcomes as well as high financial costs after kidney transplantation. Identifying and implementing strategies to reduce infections after kidney transplantation is important for improving patient outcomes. This study seeks to determine the feasibility of body surface area-based dosing of mycophenolate compared to standard dosing of mycophenolate in a pilot randomized controlled trial.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Body surface area-based dosing of mycophenolate
Standard (fixed) dosing of mycophenolate
University of California, San Francisco
San Francisco, California, United States
Enrollment rate in a trial of BSA-based vs. fixed dosing of mycophenolate
Assess the ratio of participants screened to enrolled into the study
Time frame: 6 months
Feasibility of a trial of BSA-based vs. fixed dosing of mycophenolate
Assess the rate of dropout from the study
Time frame: 6 months
Collect pilot data of efficacy in a trial of BSA-based vs. fixed dosing of mycophenolate
Collect pilot data on number of overall hospitalizations
Time frame: 6 months
Collect pilot data of efficacy in a trial of BSA-based vs. fixed dosing of mycophenolate
Collect pilot data on infectious-related hospitalizations
Time frame: 6 months
Collect pilot data of efficacy in a trial of BSA-based vs. fixed dosing of mycophenolate
Collect pilot data on incidence of leukopenia
Time frame: 6 months
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