The purpose of this study is to examine the effect of weekly dosing strategy on fracture healing.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
80
weekly subcutaneous administration of 40 ug
weekly subcutaneous administration of 40 ug
The median time of radiographic healing
A score of 13 by Modified Radiographic Union Scale for Tibia fractures (mRUST) scoring system would provide a confident assessment of union
Time frame: 0-14 weeks
Patient-Rated Wrist Evaluation
A 15-item questionnaire(PRWE) that rates wrist-related pain and disability in functional activities. The scores range from 0 (no disability) to 100 (severest disability).
Time frame: 0, 4, 6, 8, 10, 12, 14 and 16 weeks
Grip strength
Grip strength will be assessed by a dynamometer.
Time frame: 6, 8, 10, 12, 14, and 16 weeks
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