Follow-up of Critical COVID-19 Patients

Uppsala University300 enrolled

Overview

The study will follow COVID-19 patients who required intensive care after 3-6 months and one year after discharge from the ICU with functional level as well as organ function to assess recovery after COVID-19. Blood and urine will be collected for biobanking.

The study will follow COVID-19 patients who required intensive care at Uppsala University Hospital and were included in the Uppsala COVID-19 biobank. The patients will be contacted after three to six months for a first follow-up with assessment of functional level in activities of daily life, psychiatric symptoms, neurological symptoms and working capacity as well as specific organ functions. The organ functions will include circulation, respiration, coagulation, immune function and kidney function. In addition, blood and urine will be collected for biobanking.

Study Type

OBSERVATIONAL

Enrollment

300

Conditions

COVID19 ARDS AKI Circulatory Failure Coagulation Disorder Inflammatory Response

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * PCR-verified Covid-19 * Treated in ICU Exclusion Criteria: * Pregnant of breastfeeding

Locations (1)

Uppsala University Hospital

Uppsala, Sweden

RECRUITING

Outcomes

Primary Outcomes

Mortality

Death

Time frame: Within 90 days after admission to ICU.

Mortality

Death

Time frame: Within 1 year after admission to ICU.

Renal recovery

Return of renal function measured as CKD stage.

Time frame: At follow-up three to six months after ICU discharge.

Renal recovery

Return of renal function measured as CKD stage.

Time frame: At follow-up one year after ICU discharge.

Respiratory recovery

Respiratory function as assessed by a clinician