Efficacy of Biofeedback PFMT and Medication in Women With Overactive Bladder

Far Eastern Memorial Hospital140 enrolled

Overview

Medical treatment for overactive bladder is acceptable widely. However, the effect of drug treatment is different due to compliance and side effect of the drug. Biofeedback-assisted pelvic floor muscle training (PFMT) is the first line recommendation for overactive bladder. The slow effect of biofeedback-assisted pelvic floor muscle training leads to low motivation for continuous treatment and results in compliance difference. This slow effect also changes the degree of improvement in the treatment of overactive bladder. This study is designed to evaluate the efficacy of combination therapy for treatment of female overactive bladder.

Participant will be prescribed with oral medication in combination with biofeedback-assisted pelvic floor muscle training (PFMT) for the first month. Participant will continue to have biofeedback assisted PFMT for another two months without oral medication. The investigators expected that combination therapy will improve the compliance and severity of symptoms in women with overactive bladder.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

140

Conditions

Overactive Bladder

Interventions

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. overactivity bladder for more than 3 months 2. more then 20 year old,less then 85 year old and acceptable to receive vaginal examination 3. need to match schedule with the investigator's clinic for 5 times,followed by individual therapy, each takes about 30 to 60 minutes, a total of 12 weeks of pelvic floor muscle exercises Exclusion Criteria: 1. Suffering from systemic neuromuscular diseases, such as stroke, spinal cord injury, peripheral neuropathy, etc. 2. Glaucoma 3. Kidney disease 4. Liver disease 5. Patients with cardiac rhythm devices. 6. Insufficient cognitive function, unable to cooperate with pelvic floor muscle exercises. 7. Women during pregnancy. 8. Maternity within six weeks after delivery

Outcomes

Primary Outcomes

3-Day Voiding Diary

to record urinary output, fluid consumed, and urinary leakage (if applicable) for 3 complete 24-hour periods (they do not have to be consecutive days).

Time frame: Baseline through study completion, an average of 12 weeks.

Symptom Distress scale(SDS)

the degree of discomfort from the specific symptoms being experienced, as perceived by the participants, consists of 23 items.The scale scored between 1 (best) and 5 (worst) .