To investigate whether laparoscopic ileocecus-sparing right hemicolectomy is feasible and oncologically safe
Our study is a single arm, single center clinical trial. The enrolled patients will accept laparoscopic ileocecus-sparing right hemicolectomy. The primary endpoint: postoperative complications, 1-year local recurrence. The second endpoint: conversion to conventional right hemicolectomy, time to first flatus after surgery, number of harvested lymph nodes, 3-year disease free survival, R0 resection, Specimen morphometry
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
30
The ileocecal artery(ICA) is skeletonized. The colic branch of ICA is divided and ligated. Preserve anterior cecal artery, posterior cecal artery and ileocecal branch of ICA. Divide and ligate the right colic artery(RCA) and middle colic artery(MCA) at their roots. Dissect the lymph nodes surrounding the ICA, RCA and MCA accordingly. Head-to-Head colocolic anastomois is done, with circular stapler via making an opening at the bottom of cecum.
The Second Affiliated Hospital of Zhejiang University
Hangzhou, Zhejiang, China
Postoperative complications
Postoperative complications used to calculate the Comprehensive Complication Index (CCI) will be recorded
Time frame: up to 90 days after surgery
1-year local recurrence
rate of local recurrence one year after surgery, including anastomotic recurrence, recurrence around ileocolic vessels and surgical trunk of superior mesenteric vein,
Time frame: 7 days after surgery
Conversion to conventional right hemicolectomy
the rate of conversion to conventional right hemicolectomy
Time frame: 1 day of surgery
Time to first flatus after surgery
days from a colectomy procedure to first occurrence of flatus during subject's postoperative recovery
Time frame: up to 7 days after surgery
Number of harvested lymph nodes
Number of harvested Lymph nodes according to the pathological report
Time frame: up to 1 week after surgery
R0 resection
Rate of resection without any affected margins during the surgical procedure according to the pathological report
Time frame: up to 1 week after surgery
Specimen morphometry
The gross dimensions of resected specimen: length, the distal and proximal resection margins distance, vascular pedicle length
Time frame: within 30 days
3-year disease free survival
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the time from enrollment until disease relapse or death from any cause 3 years after surgery
Time frame: 3 years