Safety, Tolerability, and Pharmacokinetics Study of Human Monoclonal Antibody BRII-198

Inclusion Criteria: * Subject must be 18 to 49 years of age inclusive; * Body weight ≤100 kg and body mass index (BMI) within the range of 19.0-24.0kg/m2 (inclusive); * Male or female; Exclusion Criteria: * Any clinically significant chronic or acute medical condition that makes the volunteer unsuitable for participation; * A history of significant hypersensitivity, intolerance, or allergy to any drug compound; * History of alcohol or other substance abuse;