Management of postoperative pain in 2020 remains a challenge for anesthesiologists in the perioperative period. Lidocaine is an amide local anesthetic, it is one of the oldest adjuvant analgesics and is known to possess analgesic, anti-hyperalgesic and anti-inflammatory properties. Lidocaine is proven to be as effective as epidural analgesia in colorectal surgery. However, no study has evaluated the effect of a continuous lidocaine infusion for open lung resection in the post-operative period. The present study aims to evaluate the influence of IV lidocaine given during and 24 hours after surgery, on pain scores, opioid consumption, and possible benefits on patient outcome via the opioid-sparing effect in open thoracic surgery
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
60
Patients in the Lidocaine group received a bolus of lidocaine 1% 1.5mg/kg at the induction of general anesthesia followed by a continuous infusion of lidocaine 1% 2mg/kg/h just before surgical incision and continued until 24h after the surgery
Patients in Group Placebo received an equal bolus volume of normal saline solution at induction, and then a continuous infusion started before surgical incision and maintained up until 24h postoperatively
Hotel Dieu de France
Beirut, Lebanon
Opioid consumption in the post operative period
Total dose of morphine in the post operative period is measured for patients in both arms
Time frame: Doses were measured for twenty four hours in the post operative period
Pain scores at rest and at cough
Analogue visual scale ( a 10cm scale , zero representing no pain and 10 representing the worst imaginable pain)) was used to measure pain scores for each patient at rest and at cough
Time frame: Measurements were made for 24 hours in the post operative period
Pulmonary complications
Arterial partial carbon dioxide pressure (PCO2) measurements were recorded for patients in both arms
Time frame: Measurements were recorded for 24 hours in the post operative period
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.