Multimodal Postoperative Analgesia Following OSA Surgery

Bahaa Mohammed Refaie30 enrolled

Overview

Assessment of the clinical efficacy and adverse effects of multimodal analgesic regimen consisting of nalbuphine combined with ketorolac using IV continuous infusion silicon device (Accufuser) for postoperative analgesia following multilevel OSA surgeries

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Obstructive Sleep Apnea

Interventions

Nalbuphine, ketorolac, accufuserCOMBINATION_PRODUCT

multimodal analgesic regimen consisting of nalbuphine combined with ketorolac using IV continuous infusion silicon device (Accufuser)

Eligibility

Sex: ALLMin age: 30 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * physical status of American Society of Anesthesiologists (ASA) II * age between 30 - 50 years * OSA patients diagnosed by polysomnography and stop-bang questionnaire * enrolled for multilevel OSA surgery Exclusion Criteria: * history of allergy to the study drugs * history of hepatic, cardiopulmonary or renal disease * history of any chronic pain on medication * history of substance abuse * psychiatric disorder * lack of patient cooperation.

Locations (1)

Sohag faculty of medicine

Sohag, Egypt

RECRUITING

Outcomes

Primary Outcomes

Postoperative pain

visual analog pain score

Time frame: Assessment will be carried out at zero time (time to shift to PACU) .

Postoperative pain

Visual analog pain score

Time frame: Assessment will be carried out 6 hours postoperatively

Postoperative pain

Visual analog pain score

Time frame: Assessment will be carried out 12 hours postoperatively

Postoperative pain

Visual analog pain score

Time frame: Assessment will be carried out 18 hours postoperatively

Postoperative pain

Visual analog pain score

Time frame: Assessment will be carried out 24 hours postoperatively

Postoperative pain

Visual analog pain score

Time frame: Assessment will be carried out 30 hours postoperatively

Postoperative pain

Visual analog pain score

Time frame: Assessment will be carried out 36 hours postoperatively

Postoperative pain

Visual analog pain score

Time frame: Assessment will be carried out 42 hours postoperatively

Postoperative pain

Visual analog pain score

Time frame: Assessment will be carried out 48 hours postoperatively

Central Contacts

Bahaa M Refaie, MD

CONTACT

0201026887257 bahaarefaay@med.sohag.edu.eg

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.

Secondary Outcomes

Sedation level

Ramsey sedation scale

Time frame: Zero time ( time to shift to PACU)

Sedation level

Ramsey sedation scale

Time frame: 6 hours postoperatively

Sedation level

Ramsey Sedation Scale

Time frame: 12 hours postoperatively

Sedation level

Ramsey Sedation Scale

Time frame: 18 hours postoperatively

Sedation level

Ramsey Sedation Scale

Time frame: 24 hours postoperatively

Sedation level

Ramsey Sedation scale

Time frame: 30 hours postoperatively

Sedation level

Ramsey Sedation Scale

Time frame: 36 hours postoperatively

Sedation level

Ramsey Sedation Scale

Time frame: 42 hours postoperatively

Sedation level

Ramsey Sedation Ramsey Sedation Scale

Time frame: 48 hours postoperatively

incidence of adverse effects