The Effect of Time-Restricted Eating in Cardiometabolic Health

Inclusion Criteria: * body mass index 30-39.9 kg/m2 * fasting plasma glucose 100-125 mg/dl, or 2h OGTT plasma glucose 140-199 mg/dl or hemoglobin A1C 5.7-6.4% * self-reported habitual eating period \> 15 h per day Exclusion Criteria: * shift worker, recent or expected travel crossing time zones * fasting \>12 h/day more than once a week or vegan * shift worker, recent or expected travel crossing time zones * fasting \>12 h/day more than once a week or vegan * \> once a week no food intake after 1800 h * habitually waking up before 0400 h and sleeping before 2230 h * ≥ 150 min per week of structured exercise * unstable weight (\>5% change the last 2 months) * type 2 diabetes or other major chronic disease * sleep disorder * cancer in last 5 years * conditions that render subject unable to complete all testing procedures * use of medications that affect the study outcome measures or increase the risk of study procedures and that cannot be temporarily discontinued (e.g., steroids, alpha or beta adrenergic blockers or agonists, etc.) * smoking and illegal drug use * pregnant or lactating * menopause * individuals that have performed procedures involving substantial exposure to radiation in the last 12 months * gastrointestinal or bariatric surgery * unable to grant voluntary informed consent or comply with the study instructions * individuals who are not yet adults (infants, children, teenagers) * prisoners