A Hepatitis B Vaccine Challenge Study After Previous Vaxelis® Vaccination (V419-013)

Inclusion Criteria: * Is healthy (based on a review of medical history and targeted physical examination) based on the clinical judgment of the investigator. * Has participated in Protocol V419-007 and received a 3 + 1 Vaxelis® schedule or participated in Protocol V419-008 and received a 2 + 1 Vaxelis® schedule. * The participant (or legally acceptable representative if applicable) provides written informed consent/assent for the study. Exclusion Criteria: * Has a history of diagnosis (clinical, serological, or microbiological) of HBV infection. * Has a known or suspected impairment of immunological function (e.g., human immunodeficiency virus (HIV), splenectomy). * Has a known hypersensitivity to any component of the study vaccine. * Has a known or suspected blood dyscrasias, leukemia, lymphomas of any type or other malignant neoplasms affecting the haematopoietic and lymphatic system. * Has a bleeding disorder contraindicating intramuscular vaccinations. * Has received any hepatitis B vaccine after participation in Protocol V419-007 or V419-008. * Is or has an immediate family member (e.g., spouse, parent/legal guardian, sibling, or child) who is investigational site or Sponsor staff directly involved with this study.