Human Albumin and Anastomotic Leakage After Gastric Cancer Surgery

Ruijin Hospital1,049 enrolled

Overview

We investigate whether the intravenously administered human albumin is beneficial to prevent anastomotic leakage after gastric cancer surgery.

Anastomotic leakage after gastric cancer surgery is not very common but it is a very critical postoperative complication. Anastomotic leakage severely compromises the recovery after surgery. It increases the overall burden of patients and hospital resources. Postoperative mortality is higher in patients with anastomotic leakage. Human albumin is routinely administered after surgery with a unproven hypothesis that the human albumin is beneficial to prevent anastomotic leakage. We investigate whether the intravenously administered human albumin is beneficial to prevent anastomotic leakage after gastric cancer surgery.

Study Type

OBSERVATIONAL

Enrollment

1,049

Conditions

Gastric Cancer Anastomotic Leak

Interventions

Human albuminBIOLOGICAL

Patients received intravenous human albumin after gastric cancer surgery. Overall quantity of human albumin were recorded.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 90 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Histologically confirmed gastric cancer * Patients who underwent radical gastrectomy Exclusion Criteria: * Patient who did not undergo gastrectomy

Outcomes

Primary Outcomes

Comparison of the rate of anastomotic leakage

The rate of anastomotic leakage were compared among both groups

Time frame: Up to one months after the discharge of last patient

Data from ClinicalTrials.gov

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