Intrathecal Analgesia Effects on Cancer Patients Discomfort Symptoms

Inclusion criteria: * patients aged 18 and older * obligation of affiliation or beneficiary of a social security scheme * patients with cancer and refractory localized cancer pain because of drug side effects or intractable pain * localized pain in topography accessible to intrathecal analgesia (legs, abdomen and pelvis, pancoast-tobias symdrom) * patient's informed consent for the study * patient able to complete the evaluation questionnaires * estimed vital prognosis more than three month * patient with all conditions for intrathecal anagelsia Exclusion criteria: * patient with intracranial hypertension * refusal of patient to be included in the study * refusal of patient to receive intrathecal analgesia * patient with many refractory pain localizations not accessible to intrathecal analgesia