This is a prospective observational study. The purpose is to explore the effect of high altitude hypobaric hypoxia on retinal microcirculation and the change of the thickness of the retina and choroid by optical coherence tomography angiography (OCTA).
Yushu is in Qinghai-Tibet plateau, an average altitude of 4000 m. The medical staff is limited in Yushu. Zhongshan ophthalmic center, sun yat-sen university in Yushu blindness project has lasted many years. Some medical staff who arrived at Yushu will have a plateau response. The high altitude hypoxia on retinal microcirculation evaluated by OCTA has not been reported. The aim of the study is to observe the microcirculation changes after exploring a hypobaric and hypoxia environment using OCTA, and relation with the plateau response. OCTA is a non-invasive examination and could see the microcirculation of the fundus directly and quickly.
Study Type
OBSERVATIONAL
Enrollment
13
The participants will go to 4000m altitude to work for two weeks.
Liang xiaoling
Guangzhou, Guangdong, China
retinal microcirculation changes
the vascular density measured by OCTA
Time frame: 1 month
Retinal thickness changes
the retinal thickness measured by OCTA
Time frame: 1 month
Choroidal thickness changes
the subfoveal choroidal thickness measured by OCTA
Time frame: 1 month
The correlation of retinal microcirculation with the altitude illness
The relationship between retinal vascular density as measured by OCTA and the degree of altitude illness as measured by acute mountain sickness (AMS) scoring system
Time frame: 1 month
The changes of intraocular pressure
The changes of intraocular pressure measured by icare Tonometer
Time frame: 1 month
The changes of blood pressure including systolic and diastolic Blood Pressure
The changes of blood pressure measured by Blood Pressure Meter
Time frame: 1 month
The changes of blood oxygen
The changes of blood Oxygen measured by Pulse Oximeter
Time frame: 1 month
the degree of altitude illness
the degree of altitude illness was assessed by acute mountain sickness (AMS) scoring system
Time frame: 1 month
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