The purpose of the study was to determine the levels of Resolvin D1 (RVD1) in the gingival crevicular fluid (GCF) and saliva of the patients with periodontitis (P) and also to investigate the effects of non-surgical periodontal treatments (NSPTs) on its levels. A total of 26 subjects (15 P, 11 healthy) were included. Clinical periodontal measurements, GCF and saliva samples were collected from each individual at baseline and 1 month after NSPTs in P group. RVD1 levels were determined by enzyme-linked immunosorbent assay (ELISA) method.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
26
Non surgical periodontal therapy was performed to patients with peridontitis
Ordu University
Ordu, Turkey (Türkiye)
Biochemical parameter (resolvin D1)
The changes in levels of resolvin D1 after periodontal treatment determined by ELISA.
Time frame: Baseline and 1 month after NSPT
Probing pocket depth
The changes in probing pocket depth after periodontal treatment were evaluated
Time frame: Baseline and 1 month after NSPT
Clinical attachment level (CAL)
The changes in CAL after periodontal treatment were evaluated
Time frame: Baseline and 1 month after NSPT
Plaque index (PI)
The changes in PI after periodontal treatment were evaluated
Time frame: Baseline and 1 month after NSPT
Gingival index (GI)
The changes in GI after periodontal treatment were evaluated
Time frame: Baseline and 1 month after NSPT
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