Deep Learning for Classification of Scheimpflug Corneal Tomography Images

Inclusion Criteria: Keratoconus group: * Presence of a central protrusion of the cornea with Fleischer ring, Vogt striae, or both by slitlamp examination. * irregular cornea determined by distorted keratometry mires and distortion of retinoscopic red reflex or both in addition to the following topographic findings as summarized by Pińero and colleagues : * focal steepening located in a zone of protrusion surrounded by concentrically decreasing power zones * focal areas with diopteric (D) values \>47.0D * inferior- superior(I-S) asymmetry measured to be \> 1.4 D * Angling of the hemimeridians in an asymmetric or broken bowtie pattern with skewing of the steepest radial axis(SRAX) . Suspicious group: • Defined as subtle corneal tomographic changes as the aforementioned keratoconus abnormalities in the absence of slit- lamp or visual acuity changes typical of keratoconus (forme fruste keratoconus). Normal group: * Refractive surgery candidates * Refractive error of less than 8.0 D sphere * Less than 3.0 D of astigmatism * without clinical, topographic or tomographic signs of keratoconus or suspect keratoconus. Exclusion Criteria: * Systemic disease * Other corneal disease such as pellucid marginal degeneration * History of trauma * Corneal surgery such as corneal cross- linking for progressive keratoconus.