Sofosbuvir Containing Regimens in Treatment of COVID 19 Patients

Inclusion Criteria: * COVID 19 positive patients Exclusion Criteria: * COVID-19 patients with critical manifestations. * Sepsis. * Acute respiratory distress syndrome (ARDS). * Decompensated liver disease (Child-Pugh class B or C disease). * Chronic renal impairment. * Patients with blood diseases (severe anemia, thalassemia, ITP, leukemia ….). * Ischemic heart disease within the last 6 months. * Chronic pulmonary disease. * Malignancy. * Pregnancy or breastfeeding. * Hypersensitivity to sofosbuvir or ribavirin. * Patients with organ transplant. * Unwilling to participate in our study