Comparison of Two Preparations for the Study of the Colon Through Colonoscopy

Unidade Local de Saúde do Alto Ave, EPE613 enrolled

Overview

Compare the quality of bowel preparation between two groups of patients, who will undergo two different preparations: 1. Moviprep + diet; 2. Plenvu + diet

The quality of bowel preparation is essential for the success of a colonoscopy, reducing colonoscopy duration, and increasing the rate of cecal intubation and of polyp detection. There are several types of preparations available on the market and, irrespective of the choice, the split-dose regimen should be followed. A reduced volume preparation makes the process easier and more tolerable, increasing adhesion. Regarding the diet to be applied before the examination, there are no advantages to a liquid diet compared to a low fiber diet, and there is no evidence on the duration of the diet. In addition, a restrictive diet has an impact on satisfaction and also on adherence to treatment.

Study Type

OBSERVATIONAL

Enrollment

613

Conditions

Colon Cancer Colon Polyp Colon Adenoma Colon Rectal Cancer

Interventions

PLENVUDRUG

Bowel preparation for a colonoscopy

MoviPrepDRUG

Bowel preparation for a colonoscopy

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * All patients aged \> 18 years and indicated for examination requiring bowel preparation Exclusion Criteria: * Pregnant or breastfeeding women * Patients with gastroparesis or gastric obstruction. * Patients with psychiatric disorders * Severe renal impairment with CrCl \<30mL/min * Class III-IV Heart Failure * Dependence / use of laxatives * Chronic constipation (\<3 stools/week). * Uncontrolled hypertension (SBP \>170mmHg or DBP \>100mmHg) * Intestinal Obstruction * Colostomy from previous intestinal surgery * Severe ascites * Refusal of participation in the study * Patients unable to understand or respond to the satisfaction survey

Locations (1)

Hospital Senhora da Oliveira

Guimarães, Portugal

Outcomes

Primary Outcomes

Quality of bowel preparation between the two groups of patients

The colonoscopist assessed each of the 3 colon segments on the BBPS and assigned each a score of 0 to 3. Successful overall bowel preparation is defined as a BBPS score of \>6 with no individual segment scoring \<2.

Time frame: Patients were instructed to report any possible adverse events for up to 1 month after the procedure.

Secondary Outcomes

Degree of satisfaction with the two bowel preparation

The level of patient satisfaction with the 2 bowel preparation regimens was also assessed through a comparative analysis of the patient satisfaction questionnaire

Time frame: Patients were instructed to report any possible adverse events for up to 1 month after the procedure.

Quality of bowel preparation in patients who had a morning or afternoon colonoscopy and those who received written, oral and additional telephone re-education on the day before the colonoscopy versus written and oral information only.

Time frame: Patients were instructed to report any possible adverse events for up to 1 month after the procedure.

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.