A randomized clinical trial designed and intended to evaluate the efficacy of Dexamethasone and Methylprednisolone as a treatment for severe Acute Respiratory Distress Syndrome (ARDS) caused by coronavirus disease 19 (COVID-19). Our aim is to find the best option for the treatment and management of ARDS in COVID-19 patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
60
Injectable solution
Injectable solution
Chattogram General Hospital
Chittagong, Bangladesh
RECRUITINGM. Abdur Rahim Medical College Hospital
Dinajpur, Bangladesh
RECRUITINGMortality rate (In hospital)
Time frame: Following randomization 30 days.
Clinical improvement
The number of participants with "Clinical improvement" determined by the improvement of individual presenting symptoms of the COVID19; changes in radiological and laboratory values.Patient admitted in general bed requiring High Dependency Unit (HDU), and an HDU patient requiring Ventilator or Intensive care support.
Time frame: Following randomization 30 days.
Ventilator free days
Time frame: Following randomization 30 days.
Changes in Oxygen level
Oxygen saturation in the peripheral blood determined by pulse oximetry.
Time frame: Following randomization 30 days.
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