The primary endpoint was the success rate of adjuvant isonicotinic acid hydrazide (INH) and misoprostol versus misoprostol alone for medical termination of first-trimester pregnancy.
According to the American college of obstetricians and gynecologists (2005), medical abortion is an acceptable alternative for surgical procedures in pregnant women with gestational age of less than 10 weeks based on the last menstrual period Oral or vaginal misoprostol causes complete abortion in almost 85% of cases within seven days before the 12th week Adjuvant isonicotinic acid hydrazide (INH) administration with misoprostol raises the rate of complete abortion
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
240
total dose 900 mg per day for 3 days then Misoprosrol 800mcg will be given to all patients for induction of abortion
Misoprosrol 800mcg will be given to all patients for induction of abortion
Aswan University Hospital
Aswān, Egypt
number of patients with complete abortion
number of patients with complete abortion
Time frame: 12 hours
time from induction to abortion
time from induction to abortion
Time frame: 12 hours
number of the women will undergo dilatation and curettage after failed medical induction of abortion
number of the women will undergo dilatation and curettage after failed medical induction of abortion
Time frame: 12 hours
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