To compare the effectiveness of vaginal dinoprostone and vaginal Isonicotinic acid hydrazide in minimizing the pain experienced by postmenopausal patients during diagnostic office hysteroscopy and to assess the ease of insertion of hysteroscope as reported by the hysteroscopist.
hysteroscopy is commonly used in the diagnosis and treatment of intrauterine lesions such as polyps, fibroids, septa, and adhesions, and in the presence of abnormal bleeding and during the removal of an intrauterine device or foreign body. Cervical ripening is made possible by the use of medication through different routes.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
200
3 tablet of INH inserted by the patient 12 hours before the scheduled office hysteroscopy
1 vaginal tablet of dinoprostone (3mg) (prostin® E2, Pharmacia \& Upjohn, Puurs, Belgium) inserted by the patient 12 hours before the scheduled office hysteroscopy.
Aswan University Hospital
Aswān, Egypt
RECRUITINGIntensity of pain
Pain intensity will be assessed by visual analogue scale during the procedure. Visual analogue scale ranging from 0 to 10
Time frame: 10 minutes
Operative time
From the introduction of hysteroscope into the vagina till compilation of hysteroscopic examination
Time frame: 15 minutes
Pain intensity will be assessed by visual analogue scale
Pain intensity will be assessed by visual analogue scale 30 minutes after the procedure. Visual analogue scale ranging from 0 to 10
Time frame: 30 minutes after the procedure
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