Low Dose Tadalafil for Treatment of Female OAB Syndrome: Short Term Follow up.

Kasr El Aini Hospital90 enrolled

Overview

Evaluation of use of low dose tadalafil 5 mg daily for treatment of female OAB syndrome

90 female patients with overactive bladder syndrome divided into 3 groups group A subjected to daily low dose tadalafil 5 mg ,group B subjected to tolterodine and group C to placebo. They are evaluated as using OAB symptoms score for 6 months follow up

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Female Patients With Overactive Bladder Syndrome or Female Patients With Urgency or Urgency Urinary Incontinence

Interventions

Low dose tadalafil 5 mgDRUG

Efficacy of daily low dose tadalafil 5mg for treatment of female overactive bladder syndrome or urgency with or without urgency urinary incontinence

Tolterodine 4 Mg Oral Capsule, Extended ReleaseDRUG

To compare efficacy of low dose tadalafil 5 mg to tolterodine 4 mg extended release in treatment of female overactive bladder

PlaceboDRUG

Placebo drugs

Eligibility

Sex: FEMALE

Medical Language ↔ Plain English

Inclusion Criteria: * any female with overactive bladder syndrome, urgency with or without urgency urinary incontinence Exclusion Criteria: * Active Urinary tract infection * neurologic abnormality * Pure Stress urinary incontinence

Locations (1)

Samer Morsy

Cairo, Egypt

Outcomes

Primary Outcomes

Efficacy of daily low dose tadalafil 5mg in treatment of female overactive bladder syndrome: 6 months follow up

Evaluation of efficacy of tadalafil 5 mg

Time frame: 6 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.