Indiana University Gastrointestinal Motility Diagnosis Registry

Indiana University5,000 enrolled

Overview

Develop a registry (list of patients) with accurate clinical motility diagnosis. This registry will help the doctors to identify the patients with specific disease conditions. It will also help in promoting future research in gastroenterology motility disorders

Develop a registry (list of patients) of patients seen the clinics with motility disorders. Motility diagnosis based on billing diagnostic codes are not accurate. Motility diagnosis will be made by physicians with specialized in GI Motility, based on clinical consensus of diagnostic criteria. The information gathered from the database will be used to help promote future clinical research in the GI motility and Neurogastroenterology Unit at Indiana University School of Medicine. Gastrointestinal motility symptoms are very common. It encompasses a wide range of problems, such as dysphagia, heartburn, nausea, emesis, food regurgitation, abdominal distension, weight loss, postprandial bloating, constipation, and diarrhea. An accurate diagnosis is essential in order to promote cost-effective treatment and future research to benefit patients with GI motility disorders Specific Aims 1. Primary Aim: Identification of patients by accurate motility diagnosis 2. Secondary Aims: 1. To develop Patient Reported Outcome (PRO) measurements in patients with small intestinal bacterial overgrowth (SIBO) 2. To develop Patient Reported Outcome (PRO) measurements in patients with gastroparesis

Study Type

OBSERVATIONAL

Enrollment

5,000

Conditions

Eosinophilic Esophagitis Gastroesophageal Reflux Disease (GERD)Gastroparesis

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: 1. Patients who presented to the GI outpatient clinics, in-patient consult service, and outpatient endoscopy centers within the Division of Gastroenterology and Hepatology 2. Carries a diagnosis of GI motility disorder based on the diagnostic criteria listed in table Exclusion Criteria: 1\. Coexisting medical conditions that may limiting participation in clinical research trial

Outcomes

Primary Outcomes

Identification of patients by accurate motility diagnosis

Motility diagnosis will be made by physicians with specialized in GI Motility, based on consensus diagnostic criteria. The information gathered from the database will be used to help promote future clinical development and research in GI motility disorders.

Time frame: .through study completion, an average of 10 years

Secondary Outcomes

Patient Reported Outcome (PRO) Measurements in Patients with Small Intestinal Bacterial Overgrowth (SIBO)

SIBO-disease specific patient questionnaire will be compared between patients with aerodigestive tract SIBO and coliform SIBO

Time frame: through study completion, an average of 10 years

Patient Reported Outcome (PRO) Measurements in Patients with Gastroparesis

Patient Assessment of GI - Symptom (PAGI-SYM) scores will be compared between patients with emesis-predominant, dyspeptic-predominant, and regurgitation-predominant gastroparesis.