This study aims to measure diaphragmatic dysfunction with ultrasonography and nerve stimulation of the phrenicus nerve, in patients undergoing thoracic surgery for lung and esophageal cancer, and correlate measures of diaphramatic function to clinical postoperative endpoints.
Study Type
OBSERVATIONAL
Enrollment
40
Lunge lobectomy (total) Resection of esophagus cancer
Department of Anaesthesiology and Intensive Care East Section, Aarhus University Hospital
Aarhus N, Denmark
Change in excursion of the diaphragm
Ultrasonographic measure with M-mode of Diaphragmatic Excursion on right hemidiaphragm
Time frame: Prior to surgery to 14 days after surgery
Ultrasonographic measure of the difference in Intrathoracic Area
Intrathoracic Area is measured at inspiration and expiration to calculate the difference in Intrathoracic Area during breathing
Time frame: Prior to surgery to 14 days after surgery
Change in Diaphragmatic Thickening Fraction
Ultrasonographic measurement
Time frame: Prior to surgery to 14 days after surgery
Change in Intercostal Muscle Thickening Fraction
Ultrasonographic measurement
Time frame: Prior to surgery to 14 days after surgery
Change in forced expired volume within the first second (FEV1)
Spirometry
Time frame: Prior to surgery to 14 days after surgery
Change in forced vital capacity (FEV)
Spirometry
Time frame: Prior to surgery to 14 days after surgery
Change in peak flow
Spirometry
Time frame: Prior to surgery to 14 days after surgery
Change in Electromyographic measure of Maximal Diaphragmatic Response after stimulating the phrenic nerve
Time frame: Prior to surgery to 14 days after surgery
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Change in Electromyographic measure of Latency of Diaphragmatic Response after stimulating the phrenic nerve
Time frame: Prior to surgery to 14 days after surgery
Change in 6 Minutes Walk Test
Maximum Walking Distance within 6 minutes
Time frame: Prior to surgery to 14 days after surgery
Change in visual analogue scale score
Scoring system for subjective sensation of pain ranging from 0 to 10. Higher numbers signify higher pain sensations
Time frame: Prior to surgery to 14 days after surgery
Accumulated Opiod Use after Surgery
Morphine equivalents
Time frame: Prior to surgery to 14 days after surgery
Postoperative Pulmonary Complications
Comprising: 1. Pneumonia 2. Atelectasis 3. Bronchospasm 4. Hypoxemia 5. Severe Hypoxemia 6. Pleural Effusion 1 \> cm 7. Pneumothorax 8. CPAP or NIV required after 1. postoperative day
Time frame: Prior to surgery to 30 days after surgery
Admission days at the Intensive Care Unit after Surgery
Time frame: Prior to surgery to 60 days after surgery
Number of Admissions after Discharge from the Surgical Department
Time frame: Prior to surgery to 60 days after surgery
Accumulated Admission Days at any Hospital
Time frame: Prior to surgery to 60 days after surgery