A Clinical Study to Assess the Effects of KB295 in Patients With Ulcerative Colitis (UC) on Gut Microbiota Structure and Function

Inclusion Criteria: * Be male or female, ≥18 and ≤75 years of age * Confirmed diagnosis of UC (\>6 months) by endoscopy * Mild-to-moderate UC with at least 4 weeks of UC symptomatology prior to screening * Stable medication regimen for at least 2 weeks prior to screening, if on medication for UC Exclusion Criteria: * Possible or confirmed diagnosis of Crohn's disease or indeterminate disease * History of isolated distal proctitis * Use of any antidiarrheal medications within the last 1 week prior to screening * Antibiotic treatment within the past 28 days prior to screening * Any non-UC related immunosuppressive medications other than purine analogs. Systemic corticosteroids including prednisone \> 10 mg per day are excluded. * Major intra-abdominal surgery related to the bowel within 24 weeks prior to the screening period and/or planned invasive surgery/hospitalization during the study * Major medical comorbidities, or other conditions in the opinion of the PI, that might impact the patient's safety or compliance, or the interpretation of the study results * Treatment with any other investigational drugs within 28 days prior to the screening visit