To test the impacts of different exercise training programs to the cardiopulmonary function, muscle metabolism, and body mass composition
Atrial fibrillation (AF) has been a global threat due to its increasing incidence and prevalence, and also its potential complications of embolic stroke and heart failure, and therefore has a great impact on life expectancy and quality of life. AF with preserved ventricular function is associated with exercise intolerance, and the effect of physical training had shown to improve life quality and heart function in the population. However, the optimal physical training modalities and intensities are not well studies. Here we conduct a prospective, randomized, and interventional trial to investigate the effects of different exercise training programs to the burden of AF. We also exploit advanced imaging modalities, including dual x-ray absorptiometry and muscle magnetic resonance, to explore the change of body mass compositions. With this project, we will be able to explore the effects of different physical exercise modalities to the burden of AF and heart function, and also build up a best exercise training program, specific for this population.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
100
Aerobic training
Resistance training
Control physical exercise
National Taiwan University Hospital
Taipei, Taiwan
AF burden
AF burden on 14 day ECG
Time frame: 5 months
CPET/6 minute walking test
CPET/6 minute walking test
Time frame: 5 months
DEXA/muscle MRI
DEXA/muscle MRI
Time frame: 5 months
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