The purpose of this study is to identify the presence or absence of ectopic lymph node-like structures in skin lesions of patients with autoimmune bullous disease and the subtypes of the cells deposited there. In addition, this study clarifies the therapeutic effect of intralesional steroid injection in patients with pemphigus harboring ectopic lymph node-like structure.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
41
5\~20mg/ml, intralesional injection every 1 month. Number of cycles: until the lesions are clinically cleared
GangnamSeverance Hospital
Seoul, South Korea
Clinical outcome: size of lesions
The area of the lesions will be measured using the Image J program
Time frame: through study completion, an average of 1 year
The presence or absence of ectopic-lymph node-like structure by histologic evaluation
The presence of absence of ectopic-lymph node-like structure will be evaluated by histologic evaluation
Time frame: through study completion, an average of 1 year
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