Irritation Potential of Omeza Collagen Matrix Using Modified HRIPT

Inclusion Criteria: * Good general health, as assessed by medical history and brief dermal skin examination of the application site (back); * Was fully informed of the risks of entering the study and was willing to provide written consent to enter the study; * Was willing to follow study rules, which included: no sun exposure (for example; no swimming, sunbathing, or tanning beds), avoided activities that would cause excessive sweating, abstained from use of lotions, creams, or oils on the back area; * Was willing to not change current brand of personal care products such as soaps, body washes, laundry detergents, body sprays, body spritzes, etc. while participating on the study; * Was willing and able to practice an acceptable measure of contraception (i.e. birth control medication for at least 3 months prior, condom with spermicide or birth control injections,) during the study, if female of childbearing potential. To be considered female of non-childbearing potential, subject must have had a hysterectomy, tubal ligation, or had been post-menopausal for at least 1 year. Exclusion Criteria: * Clinically significant skin disease which contraindicated participation, including psoriasis, eczema, atopic dermatitis, and active cancer; * Asthma that required medication; * Insulin-dependent diabetes; * Known immunological disorders such as HIV positive, AIDS and systemic lupus * erythematosus; * Treatment for any type of cancer within the last six months; * Routine use (as defined by using more than 3 days in a week) of any anti-inflammatory drug (e.g., aspirin, ibuprofen, corticosteroids; 81 mg aspirin is acceptable), immunosuppressive drugs, antihistamine medication (steroid nose drops and/or eye drops are acceptable) or over-the-counter pain medication that was ingested in quantities exceeding label instructions; * Use of topical drugs at patch site; * Pregnancy, lactation, or planning a pregnancy (confirmed by a urine pregnancy test administered to females of childbearing potential); * Medical condition which, in the Investigator's judgement, made the subject * ineligible or placed the subject at undue risk; * Participation in any patch test for irritation or sensitization within the last four weeks; * Dermatological aberrations in or around test sites which included sunburn, extremely deep tans, uneven skin tones, tattoos, scars, excessive hair, numerous freckles, or any other disfiguration of the test site; * Confirmed allergy to adhesives, bandages, or ingredients in OmezaTM Collagen Matrix; * History of anaphylaxis to matrix ingredients (e.g. fish, palm oil, hemp oil, beeswax).