The study is examining differences in central arterial stiffness, orthostatic changes in blood pressure, norepinephrine, and plasma renin in individuals with spinal cord injury compared with age-matched uninjured controls.
The study is examining differences in central arterial stiffness, orthostatic changes in blood pressure, norepinephrine, and plasma renin in individuals with spinal cord injury compared with age-matched uninjured controls. Arterial stiffness and blood pressure will be collected in the laying down position. A blood sample of norepinephrine and plasma renin will also be collected. The participant will tilt to 30, 45 and 60 degrees for 10 minutes at each angel. Blood pressure and heart rate will be monitored at each angle. Another blood sample of renin and norepinephrine will be collected at the end of 10 minutes at 60 degrees.
Study Type
OBSERVATIONAL
Enrollment
33
Spinal Cord Injury
James J Peters VAMC
The Bronx, New York, United States
Pulse Wave Velocity (m/s)
Determine average pulse wave velocity among the three groups.
Time frame: 2 years
Systolic Blood Pressure (mmHg)
Determine differences in blood pressure among groups
Time frame: 2 years
Plasma Renin (pg/ml)
Determine differences in plasma renin among the groups
Time frame: 2 years
Norepinephrine (pg/ml)
Determine differences in plasma norepinephrine among the groups.
Time frame: 2 years
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