CT Abnormalities Evocative of Lung Infection Are Associated With Lower 18F-FDG Uptake in Confirmed COVID-19 Patients

Central Hospital, Nancy, France22 enrolled

Overview

CT signs that are evocative of lung COVID-19 infections have been extensively described, whereas 18F-FDG-PET signs have not. Our current study aimed to identify specific COVID-19 18F-FDG-PET signs in patients that were (i) suspected to have a lung infection based on 18F-FDG-PET/CT recorded during the COVID-19 outbreak and (ii) whose COVID-19 diagnosis was definitely established or excluded by appropriate viral testing.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Presence of COVID-19 Compatible CT Abnormalities

Interventions

PET-CT of 18F-FDGDIAGNOSTIC_TEST

Whole-body 18F-FDG-PET/CT was performed on a digital hybrid system (Vereos, Philips®)

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patient coming to nuclear medicine for 18F-flurodesoxyglucose (FDG) positron emission tomography computed tomography (PET-CT) with suspicion of lung involvement * patient affiliated to a social security scheme or equivalent * adult patient having been informed of the study Exclusion Criteria: * patient with a negative covid 19 test

Locations (1)

CHRU of Nancy

Vandœuvre-lès-Nancy, Grand Est, France

Outcomes

Primary Outcomes

Visual analysis of pulmonary lobes

Visual analysis of the pulmonary lobes by calculating a extent score for each patient

Time frame: 1 day

Secondary Outcomes

Measurement of metabolic activity

Measurement of metabolic activity with SUV max of lung areas with CT abnormalities

Time frame: 1 day

Data from ClinicalTrials.gov

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