Circulating " Cancer Cells / Macrophage " HYbrid Cells in Patients With Sarcoma?

Inclusion Criteria: 1. Patient with one of the following subtypes of soft tissue or bone sarcomas: leiomyosarcoma, dedifferentiated liposarcoma, myxoid liposarcoma, synovialosarcoma, osteosarcoma, Ewing's sarcoma. 2. Diagnosis of sarcoma histologically confirmed by the RRePS network (Réseau de Référence en Pathologie des Sarcomes et des Viscères) 3. Age ≥ 18 years old. 4. Localized or metastatic disease or recurrent disease. 5. Patient who has not yet initiated specific treatment for sarcoma. 6. Patient affiliated to a Social Health Insurance in France. 7. Patient having signed informed consent prior to inclusion in the study and prior to any specific study procedures. Exclusion Criteria: 1. Patient with any other histological subtype of sarcoma, including pleomorphic sarcoma. 2. Associated pathology(s) that may prevent the proper conduct of the procedure under consideration. 3. Pregnant or breastfeeding woman. 4. Any psychological, family, geographical or sociological condition that prevents compliance with the medical follow-up and/or procedures of the study protocol. 5. Patient who has forfeited his/her freedom by administrative or legal award or who is under legal protection (curatorship and guardianship, protection of justice).