Helicobacter Pylori Eradication and Irritable Bowel Syndrome: A Prospective Study

Assiut University100 enrolled

Overview

H. Pylori is frequently observed in patients with irritable bowel syndrome(IBS). However, the effect of H. pylori eradication on IBS is not clear.

Patients with IBS symptoms using Rome IV criteria will be included. Testing for H. pylori will be done. Patients with H. pylori will receive triple therapy and followed after two weeks for eradication and assessment of IBS symptoms.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

100

Conditions

Irritable Bowel Syndrome

Interventions

Triple therapy for H.pyloriDRUG

Triple therapy of proton pump inhibitors, clarithromycin and metronidazole.

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * Patients newly diagnosed with IBS and H.pylori Exclusion Criteria: * Patients received previous treatment of H.pylori * Patients receiving treatment for IBS.

Outcomes

Primary Outcomes

Questionnaire for Rome IV criteria

Symptoms of IBS

Time frame: 2 weeks

Secondary Outcomes

Quality of life questionnaire

Quality of life.

Time frame: 2 weeks

Data from ClinicalTrials.gov

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