to assess and compare the performance two approaches for sentinel lymph node ( SLND) biopsy
Endometrial cancer is the most common gynecologic cancer. Most patients diagnosed in early stages because cancer causes remarkable symptoms such as postmenopausal or abnormal bleeding. Mostly, it does not spread, detects no metastasis. Endometrial carcinoma is surgically staged. Laparotomy or minimally invasive surgery can be performed for treatment and staging. Patients have been operated for staging surgery, have a larger surgical incision, longer operation period, more complications, more intensive care units need. Nowadays, researchers show us that there is no difference in overall survival and prognosis between surgery with or without lymphadenectomy in endometrial cancer. With all these improvements in gynecologic oncology leads us to minimally invasive surgery. Patients undergo sentinel lymph node detection by using fluorescence imaging with an indocyanine green solution. Two different ways used to assess SLND. The first group who the cervix is injected superficially with 1 mL of ICG ( indocyanine green) at 4 and 8 o'clock quadrans. The second group who ICG has injected the uterine cavity during hysteroscopy. The investigator's aim is to assess and compare the performance of two approaches for sentinel lymph node ( SLND) biopsy.
Study Type
OBSERVATIONAL
Enrollment
106
Indocyanine green (ICG) is a cyanine dye used in medical diagnostics.ICG is a fluorescent dye that is used in medicine as an indicator substance.
Cihan Comba
Istanbul, Sultangazi, Turkey (Türkiye)
RECRUITINGSLN detecting rate
SLN is the first lymph node to spread tumoral cells.
Time frame: 1 year
Overall survival
Overall survival of endometrial cancer measures as five years
Time frame: 5 years
Disease free survival
Disease free survival can be describe with no tumor occurance after surgery
Time frame: 5 years
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