Shivering and Glucose Homeostasis

Inclusion Criteria: * Signed informed consent * Caucasian * Healthy (as determined by dependent physician based on medical questionnaire) * Man, or postmenopausal (defined as at least 1year post cessation of menses) woman * Aged 40 - 75 years at the start of the study * BMI 27 and 35 kg/m2 * Stable dietary habits (no weight loss or gain \>3kg in the past 3 months) Exclusion Criteria: * \- Not meeting all inclusion criteria * Medication use known to hamper subject's safety during study procedures * Co-morbidities to which the intervention or program that may pose as a complicating factor * Subjects diagnosed with cardiovascular diseases or cancer * Fasting plasma glucose ≥ 7.0 mmol/l * Haemoglobin \< 7.8 mmol/l for women, or \< 8.4 mmol/l for men * Previously diagnosed with type 2 diabetes * Abuse alcohol/drug abuse * Subjects who do not want to be informed about unexpected medical findings during the screening/study or do not wish that their physician is informed. * Engagement in structured exercise \> 2h per week * Participation in another biomedical study within 1 month before the first study * Smoking * Cold-acclimated, such as takes daily extended cold baths, works in a refrigerated environment, or regular cold-water swimming within 1 month of starting the study