The aim of this study is to determine if microRNA's have role in predicting multicentricity in breast cancer. If a specific microRNA will be found to be related with multicentricity, it will help us to make appropriate decisions on the treatment of patients with multicentric breast cancer.
In the study that will be held at Bezmialem Vakif University Medical Faculty, General Surgery Department, 20 unifocal and 20 multifocal breast cancer patients will be included. Tissues will be taken from both tumoral and normal breast tissues and they will be saved in microRNA later solution under -80°C. Then, 84 microRNA's will be studied in these tissues to see if they express any of these microRNA's.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
DIAGNOSTIC
Masking
NONE
Enrollment
57
miRNA's expressed in breast cancer
Bezmialem Vakif University
Istanbul, Turkey (Türkiye)
MicroRNA's in multicentric breast cancer
Evaluation of 84 microRNA's in patients with multicentric breast cancer
Time frame: April 2014
Treatment plan according to the detected microRNA in patients with multicentric breast cancer
If a specific microRNA will be detected in patients with multicentric breast cancer, treatment plan will be individualized according to the detected microRNA
Time frame: April 2014
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