This rSO2 study is a prospective clinical study. The purpose of the rSO2 study is to investigate whether there is a correlation between the intraoperative cerebral and renal tissue oxygen saturation and the incidence of developmental and socioemotional delay after living donor liver transplantation for children. This study will also investigate whether intraoperative cerebral and renal tissue oxygen saturation are related to postoperative complications.
There is high incidence of developmental and socioemotional delay and postoperative complications in pediatric living donor liver transplantation patients. In this prospective observational clinical study, the investigators aim to investigate the correlation between the intraoperative cerebral and renal tissue oxygen saturation and the incidence of developmental and socioemotional delay and postoperative complications. This study will enroll patients aged from 6 to 36 months old who are scheduled for elective standard living-donor liver transplantation and have signed informed consent before the surgery.
Study Type
OBSERVATIONAL
Enrollment
123
Renji Hospital
Pudong, Shanghai Municipality, China
RECRUITINGDevelopmental delay
Developmental delay will be measured using Age and Stage Questionnaire(ASQ) after surgery.
Time frame: 10days
Developmental delay
Developmental delay will be measured using Age and Stage Questionnaire(ASQ) after surgery.
Time frame: 1 month
Developmental delay
Developmental delay will be measured using Age and Stage Questionnaire(ASQ) after surgery.
Time frame: 3 months
Developmental delay
Developmental delay will be measured using Age and Stage Questionnaire(ASQ) after surgery.
Time frame: 6 months
Developmental delay
Developmental delay will be measured using Age and Stage Questionnaire(ASQ) after surgery.
Time frame: 1 year
Developmental delay
Developmental delay will be measured using Age and Stage Questionnaire(ASQ) after surgery.
Time frame: 2 years
Developmental delay
Developmental delay will be measured using Age and Stage Questionnaire(ASQ) after surgery.
Time frame: 3 years
Socioemotional Delay
Socioemotional Delay will be measured using Age and Stage Questionnaire: Social Emotional(ASQ-SE) after surgery.
Time frame: 10days
Socioemotional Delay
Socioemotional Delay will be measured using Age and Stage Questionnaire: Social Emotional(ASQ-SE) after surgery.
Time frame: 1 month
Socioemotional Delay
Socioemotional Delay will be measured using Age and Stage Questionnaire: Social Emotional(ASQ-SE) after surgery.
Time frame: 3 months
Socioemotional Delay
Socioemotional Delay will be measured using Age and Stage Questionnaire: Social Emotional(ASQ-SE) after surgery.
Time frame: 6 months
Socioemotional Delay
Socioemotional Delay will be measured using Age and Stage Questionnaire: Social Emotional(ASQ-SE) after surgery.
Time frame: 1 year
Socioemotional Delay
Socioemotional Delay will be measured using Age and Stage Questionnaire: Social Emotional(ASQ-SE) after surgery.
Time frame: 2 years
Socioemotional Delay
Socioemotional Delay will be measured using Age and Stage Questionnaire: Social Emotional(ASQ-SE) after surgery.
Time frame: 3 years
Postoperative complications
Postoperative complications including Cardiovascular system, respiratory system, digestive system, urinary system, blood system will be screened.
Time frame: 30 days
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