Dumping syndrome (DS) is frequent in oesophageal atresia (29%). In causing hypoglycaemia, it can be dangerous for neonates. Mechanisms of DS are actually partialy understood. This is also an affection difficult to diagnose, because it only occurs after meals and can be inconstantly present. To date, their is only symptomatic treatment for DS. This study aims to understand its pathological mechanisms so as to better treat it and avoid its consequences. Oesophageal atresia patients enrolled in this study will benefit from a continuous glycemic monitoring, a continuous cardiac monitoring, and an a gastric emptying scintigraphy at the age of 3 months
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
OTHER
Masking
NONE
Enrollment
15
Continuous glycaemia monitoring,
Fasting administration of a Technecium-labelled milk bottle and quantification of the remaining radioactivity by a camera every 30 minutes for 4 hours.
continuous cardiac monitoring
Hôpital Jeanne de Flandres
Lille, France
NOT_YET_RECRUITINGHôpital Jeanne de Flandre - Pôle enfant, CHU de Lille
Lille, France
RECRUITINGAbnormal glycaemia associated with vagal hypertonia
Composite criteria: association between abnormal glycaemia (high or low) and variations of cardiac frequency
Time frame: At least once during the 48 hours monitoring
Abnormal glycaemia associated with abnormal gastric emptying
Composite criteria: association between abnormal glycaemia (high or low) and abnormal gastric emptying study
Time frame: At least once during the 48 hours monitoring
Persistance of dumping syndrome
measured by a gastric emptying scintigraphy
Time frame: At the age of 6 months
Tolerance of glucose monitoring
Occurrence of side effects or technical issues during monitoring
Time frame: At least once during the 48 hours monitoring
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