Clinical exploring study of Weiyang Yuping Decoction in preventing acute attacks of mild to moderate intermittent asthma Based on the theory of "Preventing disease from exacerbating" in Chinese medicine.
Based on the preliminary clinical and basic research, this project intends to highly optimize and integrate the TCM treatment of disease theory with the current methods to form two preventive treatment plans, one treatment group was given Weiyang Yupingfang Granules orally for 1 month on the "Sanfu"days and on the "Sanjiu" days each year for a total of 2 months one year; the other treatment group was given Weiyang Yupingfang Granules orally for 1 month in the first month of each quarter in the four quarters of the year, for a total of 4 months one year.; Comparing the effect of prevention and treatment of mild to moderate intermittent asthma exacerbations of the two prevention methods , provides new ideas for the prevention and treatment of bronchial asthma in the future, and further improves bronchial The level of prevention and treatment of asthma.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
84
Weiyang Yuping fang is a combination of the classic ancient Yuping dispersion used to prevent qi deficiency and susceptibility and Bushen Naqi granules optimized formated by Professor Shao Changrong's experience in treating chronic cough and asthma.
Longhua Hospital Affiliated Shanghai University of TCM
Shanghai, Shanghai Municipality, China
Annual severe asthma exacerbation rate
Measured the change from Baseline of annual severe asthma exacerbation rate
Time frame: up to 12 months after treatment
Time to first severe asthma exacerbation
Record the time of the patient's first severe asthma exacerbation after treatment
Time frame: up to 12 months after treatment
Average change from baseline in pre-dose FEV1
Measured the change from Baseline of forced expiratory volume in the first second
Time frame: up to 24 months
Average change from baseline in pre-dose PEF
Measured the change from Baseline of peak expiratory flow
Time frame: up to 24 months
Average change from baseline in Asthma Control Questionnaire
Measured the change from Baseline of Asthma Control Questionnaire (5-item version) - ACQ-5 score
Time frame: up to 12 months after treatment
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.