Pain Control Differences Between Oxycodone and Ibuprofen in Children With Isolated Forearm Injuries

Washington University School of Medicine

Overview

Children presenting to the Emergency Room with the chief complaint of forearm injury and/or pain will be randomized to receive oral Oxycodone or Ibuprofen to control pain.

A randomized, blinded cohort study. Consented patients will be randomized to receive either ibuprofen or oxycodone after initial RN patient assessment in Emergency Department Triage determines a need for radiographs to evaluate for possible forearm fracture. Pain assessment scores will be determined at Triage and at 30-minute intervals throughout the patient's course until the patient is discharged home or additional analgesic medication is administered.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Conditions

Forearm Injuries Pain, Acute Pediatric ALL

Interventions

OxycodoneDRUG

oxycodone 0.2mg/kg, max 10mg to be administered, randomized between that and Ibuprofen

IbuprofenDRUG

ibuprofen 10mg/kg, max 800mg, randomized between that and Oxycodone

Eligibility

Sex: ALLMin age: 6 YearsMax age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. 6 to 17 year old children presenting for care in the St. Louis Children's Hospital Emergency Department 2. Suspected acute (within 24 hours) isolated forearm fracture at the time of initial Triage assessment 3. American Society of Anesthesiologist physical status (ASA-PS) classification of I or II 4. Child with parent or legal guardian. Exclusion Criteria: 1. Multiple injuries 2. Known adverse reaction to either ibuprofen or oxycodone pts with abnormal bones or metabolic conditions that affect bones 3. Administration of any opioid within 2 hours prior to presentation 4. Non-English speaking 5. Foster care, police custody, presenting without legal guardian

Outcomes

Primary Outcomes

Pain change/difference

An appreciable change in pain scores (by 2 points) from presentation to discharge

Time frame: 180 minutes total

Data from ClinicalTrials.gov

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